The 5th Generation of Skin Boosters Is Here

For years, the aesthetic and medical worlds have been chasing the same goal: skin that looks alive. Not plumped. Not synthetic. Not stretched. Alive.

We’ve come a long way. From basic hydration to bio-regeneration, the evolution of skin boosters reads like a timeline of innovation. But here’s the truth: each generation, while impressive, has leaned heavily on external factors. Synthetic fillers. Extracted DNA. Lab-grown peptides.

Now, the industry is shifting.

Enter: 5th Generation NAD+ Skin Boosters

How We Got Here: A Fast Timeline.

Let’s take a moment to recognize how far we’ve come.

1st Generation: Hyaluronic Acid (HA)

Hydration and instant volume were the heroes here. HA worked fast. But it was cross-linked to stay put which meant it disrupted the skin’s natural rhythm. Great for a glow. Not so great for long-term health.

2nd Generation: PDRN (Polydeoxyribonucleotide)

Derived from salmon DNA, PDRN introduced regeneration and anti-inflammatory benefits. But again, it came from the outside.

3rd Generation: Peptides & Growth Factors

These upped the ante with support for elasticity, collagen, and general skin vitality. Although helpful, most were synthetic or supplemental.

4th Generation: Exosomes

These microscopic messengers brought a new focus to cellular signaling and tissue repair. A biotech breakthrough. But they raised eyebrows, too. Too complex to extract, hard to regulate, and often misunderstood.

And the Common Thread?

All four generations, for all their success, are based on external solutions. We’ve been adding things in, not waking things up.

Now Meet the 5th Generation: NAD+

This is the moment everything changes.

NAD+ (Nicotinamide Adenine Dinucleotide) is not an additive.

• It’s not harvested.
• It’s not synthetic.
• It’s not foreign.

It’s already in your body.

NAD+ is a coenzyme found in every living cell. It’s responsible for powering countless biological processes, from energy production to DNA repair. And here’s the kicker: our levels of NAD+ drop dramatically as we age. By the time you’re 40, you may have less than half of what you had at 20.

Low NAD+ = low energy, slow repair, tired-looking skin.

So instead of injecting volume, inflammation control, or synthetic signals, what if we could restore the molecule that powers cellular rejuvenation itself?

That’s what makes NAD+ a revolution.

Why NAD+ Is Different

Unlike anything before it, NAD+ boosters aren’t just working on the surface. They’re tapping into the skin’s own regenerative intelligence. It’s like flipping the switch on a backup power source your skin forgot it had.

• Benefits reported include:
• Increased collagen production
• Improved texture and tone
• Reduced oxidative stress
• Faster cellular repair
• More vibrant, resilient skin

This time: we’re not borrowing from salmon, synthesizing peptides, or mimicking natural signals. We’re reactivating what’s ours.

The Future of Skin Isn’t Added — It’s Activated

NAD+ doesn’t promise overnight miracles. It promises something deeper: the restoration of cellular function. A return to our body's natural processes. A new way forward that honors the body's inner glow.

This isn’t the next big trend. This is the future of aesthetic medicine — and it’s already inside you.